Tolazoline HCl

• CAT Number: A000457
• CAS Number: 59-97-2
• Molecular Formula: C10H12N2 • HCl
• Molecular Weight: 196.67
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO > 10 mM
• Storage: 3 years -20C powder
• IUPAC Name: 2-benzyl-4,5-dihydro-1H-imidazole;hydrochloride
• InChI: InChI=1S/C10H12N2.ClH/c1-2-4-9(5-3-1)8-10-11-6-7-12-10;/h1-5H,6-8H2,(H,11,12);1H
• InChIKey: RHTNTTODYGNRSP-UHFFFAOYSA-N
• SMILES: C1CN=C(N1)CC2=CC=CC=C2.Cl

Tolazoline HCl(CAT: A000457) is a non-selective α-adrenergic receptor antagonist with vasodilatory properties. By blocking α-adrenergic receptors, it reduces vascular resistance and improves blood flow, making it useful for treating conditions such as persistent pulmonary hypertension of the newborn (PPHN). Tolazoline also has mild histamine-like effects, which can contribute to its vasodilatory action. It is widely studied in cardiovascular pharmacology for its role in regulating vascular tone and investigating adrenergic signaling pathways. Additionally, Tolazoline HCl has applications in diagnostic procedures, such as enhancing the visualization of blood vessels during angiography. Its mechanism provides insights into adrenergic receptor function and vascular regulation.