Tolvaptan-d7

• CAT Number: S000539
• CAS Number: 1246818-18-7
• Molecular Formula: C26H18D7ClN2O3
• Molecular Weight: 455.98
• Purity: ≥95%
• IUPAC Name: N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2,3,4,5-tetradeuterio-6-(trideuteriomethyl)benzamide
• InChI: InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)/i1D3,3D,4D,6D,7D
• InChIKey: GYHCTFXIZSNGJT-FFQSSJIFSA-N
• SMILES: CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C

Tolvaptan-d7（Cat No.:S000539） is a deuterated version of tolvaptan, where seven hydrogen atoms are replaced with deuterium. Tolvaptan is a selective vasopressin receptor 2 antagonist used primarily to treat conditions like hyponatremia (low blood sodium levels) and polycystic kidney disease. By blocking the action of vasopressin, it helps to reduce water retention without causing loss of sodium, thus correcting sodium levels in the body. The deuterated form, Tolvaptan-d7, offers enhanced metabolic stability, making it valuable for pharmacokinetic and metabolic research to understand the drug’s behavior and improve its clinical efficacy and safety profiles.