For research use only. Not for therapeutic Use.
Tomatidine (Cat.No:I004861) is a naturally occurring steroidal alkaloid found in tomatoes. It has gained attention for its potential health benefits, including its anti-inflammatory and muscle-building properties. Tomatidine has been studied for its role in promoting muscle growth and reducing muscle atrophy, making it a promising compound in the field of sports nutrition and muscle-related diseases.
| Catalog Number | I004861 |
| CAS Number | 77-59-8 |
| Molecular Formula | C27H45NO2 |
| Purity | ≥95% |
| Target | target: ERK[1], Akt[1], NF-κB[1]; |
| Solubility | DMSO |
| Storage | Store at -20°C |
| IUPAC Name | (1R,2S,4S,5'S,6S,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-piperidine]-16-ol |
| InChI | InChI=1S/C27H45NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28-29H,5-15H2,1-4H3/t16-,17-,18-,19-,20+,21-,22-,23-,24-,25-,26-,27-/m0/s1 |
| InChIKey | XYNPYHXGMWJBLV-VXPJTDKGSA-N |
| SMILES | C[C@H]1CC[C@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C)C)NC1 |
| Reference | <p style=/line-height:25px/> <br>[2]. Dyle MC et al. Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy. J Biol Chem. 2014 May 23;289(21):14913-24. <br>[3]. Yan KH et al. Tomatidine inhibits invasion of human lung adenocarcinoma cell A549 by reducing matrix metalloproteinases expression. Chem Biol Interact. 2013 May 25;203(3):580-7. </p> |
