Tomaymycin DM

• CAT Number: I043487
• CAS Number: 945490-09-5
• Molecular Formula: C14H14N2O3
• Molecular Weight: 258.27
• Purity: ≥95%
• Synonyms: (6aS)-3-hydroxy-2-methoxy-8-methylidene-7,9-dihydro-6aH-pyrrolo[2,1-c][1,4]benzodiazepin-11-one
• InChI: InChI=1S/C14H14N2O3/c1-8-3-9-6-15-11-5-12(17)13(19-2)4-10(11)14(18)16(9)7-8/h4-6,9,17H,1,3,7H2,2H3/t9-/m0/s1
• InChIKey: GXKVYHPROGIVCL-VIFPVBQESA-N
• SMILES: COC1=C(C=C2C(=C1)C(=O)N3CC(=C)C[C@H]3C=N2)O

Tomaymycin DM（Cat No.:I043487）is a derivative of tomaymycin, an antibiotic produced by Streptomyces species, known for its potent antitumor and antibacterial properties. Tomaymycin DM exhibits enhanced cytotoxicity, making it a promising candidate for cancer treatment, particularly in targeting solid tumors. Its mechanism of action involves DNA intercalation and inhibition of DNA and RNA synthesis, leading to cell cycle arrest and apoptosis in cancer cells. Preclinical studies suggest that Tomaymycin DM has potential for overcoming resistance to conventional chemotherapies, and ongoing research aims to evaluate its therapeutic efficacy and safety in clinical settings.