For research use only. Not for therapeutic Use.
Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1].
Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[2].
| Catalog Number | I044901 |
| CAS Number | 41743-74-2 |
| Synonyms | 1,10-dihydroxy-7-methoxy-3-methylbenzo[g]isochromen-9-one |
| Molecular Formula | C15H12O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H12O5/c1-7-3-8-4-9-5-10(19-2)6-11(16)12(9)14(17)13(8)15(18)20-7/h3-6,17-18H,1-2H3 |
| InChIKey | NFNQIVIXHYXLPG-UHFFFAOYSA-N |
| SMILES | CC1=CC2=CC3=CC(=CC(=O)C3=C(C2=C(O1)O)O)OC |
| Reference | [1]. YongtaekSeo, et al. Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Research International. Volume 97, July 2017, Pages 340-346. [2]. Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. |
