Toremifene Citrate

• CAT Number: A001055
• CAS Number: 89778-27-8
• Molecular Formula: C26H28ClNO • C6H8O7
• Molecular Weight: 598.10
• Purity: ≥95%
• Synonyms: NSC 613680
• Target: Apoptosis
• Solubility: >24.2mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
• InChI: 1S/C26H28ClNO.C6H8O7/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-16H,17-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-
• InChIKey: IWEQQRMGNVVKQW-OQKDUQJOSA-N
• SMILES: CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCl)\C2=CC=CC=C2)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Toremifene Citrate (Cat No.:A001055) is a selective estrogen receptor modulator (SERM) used primarily in the treatment of estrogen receptor-positive (ER+) breast cancer. It functions by binding to estrogen receptors and blocking estrogen-driven cell proliferation in breast tissue, while exerting estrogenic effects in other tissues like bone. Toremifene offers a favorable safety profile and is often used as an alternative to tamoxifen, especially in postmenopausal women. It is also being studied for potential benefits in prostate cancer and osteoporosis prevention.