Torsemide-d7

• CAT Number: R009781
• CAS Number: 1189375-06-1
• Molecular Formula: C16H20N4O3S
• Molecular Weight: 355.464
• Purity: ≥95%
• Synonyms: N-[[(1-Methylethyl-d7)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide; AC-4464-d7; BM-02015-d7; JDL-464-d7; Demadex-d7; Luplac-d7; Toradiur-d7; Torem-d7; Torasemide-d7; Unat-d7
• Storage: -20°C
• IUPAC Name: 1-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl)-3-[4-(3-methylanilino)pyridin-3-yl]sulfonylurea
• InChI: InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)/i1D3,2D3,11D
• InChIKey: NGBFQHCMQULJNZ-UENXPIBQSA-N
• SMILES: CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C

Torsemide-d7 is a deuterated form of torsemide, a loop diuretic used to treat edema associated with heart failure, liver disease, and kidney disease, as well as hypertension. In this version, seven hydrogen atoms are replaced with deuterium, which enhances its utility in pharmacokinetic and metabolic studies. The deuterium labeling allows for precise tracking and analysis using mass spectrometry and NMR spectroscopy, aiding researchers in understanding the drug’s absorption, distribution, metabolism, and excretion while retaining the therapeutic effects of the non-deuterated drug.