Tos-PEG1-CH2-Boc

• CAT Number: I017042
• CAS Number: 1643957-24-7
• Molecular Formula: C₁₅H₂₂O₆S
• Molecular Weight: 330.40
• Purity: ≥95%
• Target: PROTAC Linkers
• IUPAC Name: tert-butyl 2-[2-(4-methylphenyl)sulfonyloxyethoxy]acetate
• InChI: InChI=1S/C15H22O6S/c1-12-5-7-13(8-6-12)22(17,18)20-10-9-19-11-14(16)21-15(2,3)4/h5-8H,9-11H2,1-4H3
• InChIKey: ASBZYPKOIDXKMT-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCCOCC(=O)OC(C)(C)C

Tos-PEG1-CH2-Boc（Cat No.:I017042）is a chemical compound that consists of a tosyl group (Tos), a polyethylene glycol (PEG) chain with one ethylene glycol unit (PEG1), a methylene group (CH2), and a Boc (tert-butoxycarbonyl) protecting group. The tosyl group serves as a leaving group in reactions, while the PEG1 chain provides water solubility and biocompatibility, useful in drug delivery and bioconjugation. The Boc group is commonly used to protect amines during peptide synthesis. This compound is often employed in the development of bioconjugates, drug delivery systems, and targeted therapies for various biomedical applications.

Reference

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.