For research use only. Not for therapeutic Use.
Tos-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].<br>PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Catalog Number | I016903 |
| CAS Number | 850090-13-0 |
| Molecular Formula | C₁₈H₂₈O₇S |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. |
