Tos-PEG2-NH-Boc

• CAT Number: I016831
• CAS Number: 192132-77-7
• Molecular Formula: C₁₆H₂₅NO₆S
• Molecular Weight: 359.44
• Purity: ≥95%
• Target: PROTAC Linkers

Tos-PEG2-NH-Boc (CAT: I016831) is a compound consisting of a polyethylene glycol (PEG) spacer with two tosyl (tosylate) groups and a Boc (tert-butoxycarbonyl) protecting group attached to an amino group. It is commonly used as a reagent in organic synthesis and chemical modification of biomolecules. The tosyl groups can serve as leaving groups for further reactions, while the Boc protecting group helps to protect the amino group during synthetic processes. The PEG spacer provides hydrophilicity and flexibility to the molecule. Tos-PEG2-NH-Boc is often employed in the synthesis of bioconjugates and polymer-based materials.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.