Tosufloxacin Toluenesulfonate Hydrate

• CAT Number: R007736
• CAS Number: 115964-29-9
• Molecular Formula: C26H23F3N4O6S
• Molecular Weight: 576.55
• Purity: ≥95%
• Synonyms: 7-(3-Amino-1-pyrrolidinyl)-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Toluenesulfonate Hydrate; Tosufloxacin Tosylate; A-64730; T-3262; Ozax; Tosuxacin
• Target: Antibiotic
• Storage: -20°C
• IUPAC Name: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;4-methylbenzenesulfonic acid
• InChI: InChI=1S/C19H15F3N4O3.C7H8O3S/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25;1-6-2-4-7(5-3-6)11(8,9)10/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29);2-5H,1H3,(H,8,9,10)
• InChIKey: CSSQVOKOWWIUCX-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CC1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4=C(C=C(C=C4)F)F)C(=O)O)F

Tosufloxacin toluenesulfonate hydrate（Cat No.:R007736）is a broad-spectrum fluoroquinolone antibiotic used in the treatment of bacterial infections. It is the toluenesulfonate salt form of tosufloxacin, which inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication. This action prevents bacterial growth and proliferation. Tosufloxacin is effective against various Gram-positive and Gram-negative bacteria, including respiratory and urinary tract pathogens. The toluenesulfonate salt enhances its solubility and stability, while the hydrate form ensures proper dissolution. It has been studied primarily in Asia for treating infections such as pneumonia, bronchitis, and urinary tract infections.