For research use only. Not for therapeutic Use.
Tosufloxacin Tosylate Hydrate（Cat No.:I001523）is a broad-spectrum fluoroquinolone antibiotic used in the treatment of bacterial infections. It exhibits potent activity against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication. This compound is often utilized in the management of respiratory tract infections, urinary tract infections, and skin infections. Tosufloxacin Tosylate Hydrate provides effective antibacterial action with a favorable pharmacokinetic profile, making it an important option for various bacterial infections, particularly in regions with antimicrobial resistance challenges.
| Catalog Number | I001523 |
| CAS Number | 1400591-39-0 |
| Molecular Formula | C26H25F3N4O7S |
| Purity | ≥95% |
| Target | Bacterial |
| Solubility | DMSO ≥ 33 mg/mL |
| Storage | Store at -20°C |
| IUPAC Name | 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;4-methylbenzenesulfonic acid;hydrate |
| InChI | InChI=1S/C19H15F3N4O3.C7H8O3S.H2O/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25;1-6-2-4-7(5-3-6)11(8,9)10;/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29);2-5H,1H3,(H,8,9,10);1H2 |
| InChIKey | SSULTCPIIYRGFQ-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CC1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4=C(C=C(C=C4)F)F)C(=O)O)F.O |
| Reference | <p style=/line-height:25px/> <br>[2]. Deng FY et al. [Mn2+-cTMAB-sensitized fluorescent microscopic determination of tosufloxacin tosylate based on a self-ordered ring. Guang Pu Xue Yu Guang Pu Fen Xi. 2014 Feb;34(2):445-9. <br>[3]. Chu DT et al. Synthesis and biological properties of A-71497: a prodrug of tosufloxacin. Drugs Exp Clin Res, 1990, 16(9):435-43. </p> |
