Tosylate-DPA-714 is a tosylate salt form of DPA-714, a high-affinity ligand for the translocator protein (TSPO). It is used in neuroimaging to study neuroinflammation, as TSPO is upregulated in activated microglia and macrophages. The tosylate form enhances the compound’s solubility and stability, making it more suitable for in vivo imaging studies, particularly in PET scans. Tosylate-DPA-714 is instrumental in investigating neurodegenerative diseases and monitoring the efficacy of therapeutic interventions targeting inflammation in the brain.
| Catalog Number | R072316 |
| CAS Number | 958233-17-5 |
| Synonyms | <i>N</i>,<i>N</i>-Diethyl-2-(2-(4-(2-tosyloxy-1-ethoxy)phenyl)- 5,7-dimethylpyrazolo[1,5-<i>a</i>]pyrimidin-3-yl)acetamide |
| Molecular Formula | C29H34N4O5S |
| Purity | ≥95% |
