For research use only. Not for therapeutic Use.
ToxT-IN-8 (Cat No.:I037418) is a small-molecule inhibitor targeting ToxT, a key transcriptional regulator in Vibrio cholerae that controls the expression of virulence factors, including cholera toxin and toxin-coregulated pilus. By inhibiting ToxT activity, ToxT-IN-8 disrupts virulence gene expression, reducing bacterial pathogenicity. It is a valuable tool in antimicrobial research, particularly for developing novel anti-virulence strategies against cholera and other bacterial infections. ToxT-IN-8 offers potential for therapeutic intervention by disarming bacterial pathogens without exerting selective pressure for antibiotic resistance.
| Synonyms | ToxT IN-8; ToxT-IN 8; ToxT-IN-8 |
| Molecular Formula | C15H19NO2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 3-(1-Butyl-1H-indol-7-yl)propanoic acid |
| InChI | InChI=1S/C15H19NO2/c1-2-3-10-16-11-9-13-6-4-5-12(15(13)16)7-8-14(17)18/h4-6,9,11H,2-3,7-8,10H2,1H3,(H,17,18) |
| InChIKey | KWXGUKUYMNETKJ-UHFFFAOYSA-N |
| SMILES | O=C(O)CCC1=CC=CC2=C1N(CCCC)C=C2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
