For research use only. Not for therapeutic Use.
TP748,an isoxazole, is a key intermediate for fully synthetic tetracyclines[1].
A robust, cost effective and high yielding manufacturing process for enantiomerically enriched (S)-allylic amine 3, a key intermediate for fully synthetic tetracyclines have been developed[1].
| Catalog Number | I016203 |
| CAS Number | 951698-15-0 |
| Synonyms | (1S)-N,N-dimethyl-1-(3-phenylmethoxy-1,2-oxazol-5-yl)prop-2-en-1-amine |
| Molecular Formula | C15H18N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H18N2O2/c1-4-13(17(2)3)14-10-15(16-19-14)18-11-12-8-6-5-7-9-12/h4-10,13H,1,11H2,2-3H3/t13-/m0/s1 |
| InChIKey | NMTKAGBTRNHHDC-ZDUSSCGKSA-N |
| SMILES | CN(C)C(C=C)C1=CC(=NO1)OCC2=CC=CC=C2 |
| Reference | [1]. Wu-Yan Zhang, et al. Process Research and Development of TP-808: A Key Intermediate for the Manufacture of Synthetic Tetracyclines. Process Res. Dev. 2017, 21, 3, 377-386. |
