TPn-004

• CAT Number: I037443
• Molecular Formula: C13H8F3N3
• Molecular Weight: 263.22
• Purity: 98%
• Synonyms: TPn-004; TPn004; TPn 004
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 8-phenyl-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
• InChI: InChI=1S/C13H8F3N3/c14-13(15,16)10-6-11(9-4-2-1-3-5-9)12-18-17-8-19(12)7-10/h1-8H
• InChIKey: MJRGVNWVYDTECT-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=CC(=CN3C2=NN=C3)C(F)(F)F

TPn-004（Cat No.:I037443）is a novel, selective small molecule compound that has been studied for its potential in cancer therapy. It functions as a potent inhibitor of the protein poly(ADP-ribose) polymerase (PARP), which plays a crucial role in DNA repair processes. By inhibiting PARP, TPn-004 can impair the ability of cancer cells to repair DNA damage, leading to cell death, especially in tumor cells with defective DNA repair mechanisms. TPn-004 has shown promise in preclinical studies for treating various cancers, particularly those with BRCA mutations or other defects in DNA repair pathways.