For research use only. Not for therapeutic Use.
Tr-PEG3-OH (CAT: I017179) is a non-cleavable three-unit polyethylene glycol (PEG) linker that is employed in the synthesis of antibody-drug conjugates (ADCs). ADCs are a class of targeted therapeutics that combine the specificity of monoclonal antibodies with the potency of cytotoxic drugs. The Tr-PEG3-OH linker serves as a bridge between the antibody and the cytotoxic drug, facilitating the controlled delivery of the drug to the target cells while minimizing off-target effects.
| Catalog Number | I017179 |
| CAS Number | 133699-09-9 |
| Molecular Formula | C₂₅H₂₈O₄ |
| Purity | ≥95% |
| Target | ADC Linker |
| Reference | [1]. Chou CH, et al. Glycan-Directed Grafting-from Polymerization of Immunoglobulin G: Site-Selectively Modified IgG-Polymer Conjugates with Preserved Biological Activity. Biomacromolecules. 2018 Jul 9;19(7):3086-3095. |
