Tranilast trans-

• CAT Number: I004651
• CAS Number: 70806-55-2
• Molecular Formula: C18H17NO5
• Molecular Weight: 327.34
• Purity: ≥95%
• Target: Angiotensin Receptor
• Solubility: DMSO: ≥ 42 mg/mL
• Storage: Desiccate at -20C
• IUPAC Name: 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid
• InChI: InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
• InChIKey: NZHGWWWHIYHZNX-CSKARUKUSA-N
• SMILES: COC1=C(C=C(C=C1)C=CC(=O)NC2=CC=CC=C2C(=O)O)OC

Tranilast (trans-)(CAT: I004651) is an anti-inflammatory and anti-fibrotic agent widely used in pharmacological research. It functions by inhibiting the release of inflammatory mediators such as histamine, prostaglandins, and cytokines, and it suppresses the activation of fibroblasts and TGF-β signaling. Tranilast (trans-) is extensively studied for its potential therapeutic applications in allergic disorders, hypertrophic scars, keloids, and fibrotic diseases, including pulmonary and renal fibrosis. Its trans-isomeric form ensures high bioactivity and stability. With its broad pharmacological effects, Tranilast (trans-) is a valuable tool for in vitro and in vivo studies aimed at developing treatments for inflammation and fibrotic disorders.