trans-10-Heptadecenoic acid

• CAT Number: M109311
• CAS Number: 126761-43-1
• Molecular Formula: C17H32O2
• Molecular Weight: 268.43
• Purity: ≥95%
• Synonyms: (E)-heptadec-10-enoic acid
• InChI: InChI=1S/C17H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19/h7-8H,2-6,9-16H2,1H3,(H,18,19)/b8-7+
• InChIKey: GDTXICBNEOEPAZ-BQYQJAHWSA-N
• SMILES: CCCCCCC=CCCCCCCCCC(=O)O

trans-10-Heptadecenoic acid is a trans-fatty acid. trans-10-Heptadecenoic acid synthesizes polyhydroxy-chain alkanoates under the action of 2, 4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the absence of 2, 4-dienyl-CoA reductase, trans-10-Heptadecenoic acid is degraded by enyl-CoA hydratase II of the multifunctional enzyme (MFE). trans-10-Heptadecenoic acid leads to massive intracellular carbon outflow through reductase dependent and direct MFE dependent pathways[1].

Reference

[1]. Robert J, et al. Analysis of the beta-oxidation of trans-unsaturated fatty acid in recombinant Saccharomyces cerevisiae expressing a peroxisomal PHA synthase reveals the involvement of a reductase-dependent pathway. Biochim Biophys Acta. 2005 May 15;1734(2):169-77.
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