For research use only. Not for therapeutic Use.
trans-ACPD(CAT: I004545) is a compound that acts as an agonist of metabotropic glutamate receptors. It activates these receptors, leading to calcium mobilization and an inward current in cerebellar Purkinje neurons cultured in vitro. This compound is commonly used in neuroscience research to study the physiological and pharmacological properties of metabotropic glutamate receptors and their effects on neuronal signaling.
| CAS Number | 67684-64-4 |
| Synonyms | (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid |
| Molecular Formula | C7H11NO4 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | H2O: ≤ 6.2 mg/mL (Need ultrasonic) |
| Storage | Store at RT |
| Reference | <p style=/line-height:25px/> <br>[1]. Linden DJ, et al. Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. J Neurophysiol. 1994 May;71(5):1992-8. <br>[2]. Littman L, et al. Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis. J Neurochem. 1992 Nov;59(5):1893-904. <br>[3]. Córdova MM, et al. Polysaccharide glucomannan isolated from Heterodermia obscurata attenuates acute and chronic pain in mice. Carbohydr Polym. 2013 Feb 15;92(2):2058-64. |
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