trans Resveratrol 3-Sulfate Sodium Salt

• CAT Number: I013993
• CAS Number: 858127-11-4
• Molecular Formula: C14H11O6S • Na
• Molecular Weight: 330.3
• Purity: ≥95%
• Synonyms: 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol 1-(Hydrogen Sulfate) Monosodium Salt;?
• Target: Drug Metabolite
• Storage: -20°C
• IUPAC Name: [3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenyl] hydrogen sulfate;sodium
• InChI: InChI=1S/C14H12O6S.Na/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(8-11)20-21(17,18)19;/h1-9,15-16H,(H,17,18,19);/b2-1+
• InChIKey: OWGXRCOCVOPKAM-TYYBGVCCSA-M
• SMILES: C1=CC(=CC=C1C=CC2=CC(=CC(=C2)OS(=O)(=O)O)O)O.[Na]

Trans-Resveratrol 3-Sulfate Sodium Salt (CAT: I013993) is a modified form of trans-resveratrol, a natural polyphenolic compound. Its pharmacologic action and specific targets for drugs are not widely documented due to limited public information. However, trans-resveratrol, the parent compound, is known for its antioxidant and anti-inflammatory properties. It has been investigated for potential applications in cardiovascular health, cancer prevention, and longevity. The sulfate salt modification of trans-resveratrol may influence its stability and bioavailability, potentially impacting its pharmacokinetics and cellular uptake.

Reference

1.Banerjee, Sanjeev, Carlos Bueso-Ramos, and Bharat B. Aggarwal. "Suppression of 7, 12-dimethylbenz (a) anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-κB, cyclooxygenase 2, and matrix metalloprotease 9." Cancer research 62.17 (2002): 4945-4954.
2.Wang, Lai-Xi, et al. "Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity." Journal of pharmaceutical sciences 93.10 (2004): 2448-2457.
3.Provinciali, Mauro, et al. "Effect of resveratrol on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice." International journal of cancer 115.1 (2005): 36-45.