Transergan free base

• CAT Number: I037459
• CAS Number: 82-00-8
• Molecular Formula: C19H23ClN2O2S
• Molecular Weight: 378.92
• Purity: 98%
• Synonyms: Transergan; Novazine; Transergan Free Base
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 10H-Phenothiazine-10-carboxylic acid, 2-(diethylamino)ethyl ester, monohydrochloride
• InChI: InChI=1S/C19H22N2O2S.ClH/c1-3-20(4-2)13-14-23-19(22)21-15-9-5-7-11-17(15)24-18-12-8-6-10-16(18)21;/h5-12H,3-4,13-14H2,1-2H3;1H
• InChIKey: FOQGDCBIMVXYSR-UHFFFAOYSA-N
• SMILES: O=C(N1C2=C(C=CC=C2)SC3=CC=CC=C13)OCCN(CC)CC.[H]Cl

Transergan Free Base is a new spasmolytic

Reference

1: ELIASSON S, TEJNING S. Clinical trials of transergan in the parkinsonian syndrome. Acta Med Scand. 1956 Jun 9;154(5):375-9. doi: 10.1111/j.0954-6820.1956.tb14332.x. PMID: 13326279.
2: JOHNSON SR. Transergan, ett nytt spasmolyticum; klinisk prövning [Transergan, a new spasmolytic; clinical trial]. Nord Med. 1955 Feb 17;53(7):265-7. Swedish. PMID: 14356481.
3: WIEDLING S. Pharmacological and toxicological studies on beta- diethylaminoethyl phenothiazine-10-carboxylate hydrochloride, transergan, a new spasmolytic and anti-parkinsonism agent. Acta Pharmacol Toxicol (Copenh). 1957;13(1):59-79. doi: 10.1111/j.1600-0773.1957.tb00239.x. PMID: 13381503.
4: Hellem S, Persson G, Freiberg N, Nord PG, Gustafsson B, Huitfeldt B. A model for evaluating the analgesic effect of a new fixed ratio combination analgesic in patients undergoing oral surgery. Int J Oral Surg. 1979 Dec;8(6):435-42. doi: 10.1016/s0300-9785(79)80082-4. PMID: 120341.