For research use only. Not for therapeutic Use.
Transketolase-IN-2 (compound 4w) is a potent Transketolase inhibitor. Transketolase-IN-2 shows strong inhibition of Digitaria sanguinalis and Amaranthus retroflexus (over 90% at 200 mg/L and about 80% at 100 mg/L). Transketolase-IN-2 can be used in studies of weed control[1].
Transketolase-IN-2 (200 mg/L) exhibits strong inhibitory effects against DS with the root inhibition of 92% and the stem inhibition of 90%[1].
Transketolase-IN-2 (200 mg/L) exhibits strong inhibitory effects against AR with the root inhibition of 91% and the stem inhibition of 90%.
Catalog Number | I042603 |
CAS Number | 2757552-21-7 |
Synonyms | 2-[2-methyl-4-(trifluoromethyl)-1,3-thiazole-5-carbonyl]benzo[de]isoquinoline-1,3-dione |
Molecular Formula | C18H9F3N2O3S |
Purity | ≥95% |
InChI | InChI=1S/C18H9F3N2O3S/c1-8-22-14(18(19,20)21)13(27-8)17(26)23-15(24)10-6-2-4-9-5-3-7-11(12(9)10)16(23)25/h2-7H,1H3 |
InChIKey | DSBLHEOFYWPYFY-UHFFFAOYSA-N |
SMILES | CC1=NC(=C(S1)C(=O)N2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O)C(F)(F)F |
Reference | [1]. Wang YE, et al. Design, Synthesis, and Herbicidal Activity of Naphthalimide-Aroyl Hybrids as Potent Transketolase Inhibitors. J Agric Food Chem. 2022 Oct 12;70(40):12819-12829. |