trans,trans-2,4-Decadienal

• CAT Number: R058264
• CAS Number: 25152-84-5
• Molecular Formula: C10H16O
• Molecular Weight: 152.237
• Purity: ≥95%
• Synonyms: (2E,4E)-2,4-Decadienal; (2E,4E)-Deca-2,4-dienal; (2E,4E)-Decadienal; (E,E)-2,4-Decadien-1-al; (E,E)-2,4-Decadienal; 2-trans,4-trans-Decadienal; trans,trans-2,4-Decadien-1-al; trans,trans-2,4-Decadienal; trans-2,trans-4-Decadienal
• Target: Disease Research Fields
• Storage: -20°C
• IUPAC Name: (2E,4E)-deca-2,4-dienal
• InChI: InChI=1S/C10H16O/c1-2-3-4-5-6-7-8-9-10-11/h6-10H,2-5H2,1H3/b7-6+,9-8+
• InChIKey: JZQKTMZYLHNFPL-BLHCBFLLSA-N
• SMILES: CCCCCC=CC=CC=O

Lipoxygenase-<wbr></wbr>catalyzed peroxidative decomposition of unsaturated fatty acids occurs within seconds when diatoms are crushed or eaten, producing alkyls. DDA is a prominent member of this class of reactive compounds. Common ω-<wbr></wbr>6 fatty acids such as linoleic acid, dihomo-<wbr></wbr>ω-<wbr></wbr>linolenic acid, and arachidonic acid can give rise to DDA. DDA reduces the hatching rate and has a strong teratogenic effect on the eggs of pelagic copepods, at concentrations around 1 µM. In human carcinoma Caco2 cells, DDA induces cell growth arrest at around 15 µM. DDA appears to be a natural defensive chemical designed to limit the reproductive success of copepods, the main predators of diatoms. It may also be a more general inducer of apoptosis.