Trecovirsen

• CAT Number: M091317
• CAS Number: 153021-75-1
• Molecular Weight: 7776.30
• Purity: ≥95%

Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.

Reference

[1]. Séréni D, Tubiana R, Lascoux C, et al. Pharmacokinetics and tolerability of intravenous trecovirsen (GEM 91), an antisense phosphorothioate oligonucleotide, in HIV-positive subjects. J Clin Pharmacol. 1999;39(1):47-54.
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[2]. Pedziwiatr-Werbicka E, Fuentes E, Dzmitruk V, et al. Novel ‘Si-C’ carbosilane dendrimers as carriers for anti-HIV nucleic acids: studies on complexation and interaction with blood cells. Colloids Surf B Biointerfaces. 2013;109:183-189.
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