For research use only. Not for therapeutic Use.
Trepibutone(CAT: I037474) is an acidic drug that exhibits pH-independent release characteristics. This means that its release rate is not significantly affected by changes in pH levels within the physiological range. This property is desirable for certain drug formulations as it allows for consistent drug release regardless of the acidity or alkalinity of the surrounding environment. Trepibutone’s pH-independent release profile can contribute to its reliable and predictable pharmacokinetics, making it suitable for specific therapeutic applications.
Catalog Number | I037474 |
CAS Number | 41826-92-0 |
Synonyms | Trepibutone; AA149; AA 149; AA-149; Colibil, Supacal |
Molecular Formula | C16H22O6 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 2,3,4-Triethoxy-gamma-oxobenzenebutanoic acid |
InChI | InChI=1S/C16H22O6/c1-4-20-13-9-7-11(12(17)8-10-14(18)19)15(21-5-2)16(13)22-6-3/h7,9H,4-6,8,10H2,1-3H3,(H,18,19) |
InChIKey | LPUHSIHEXXRLQW-UHFFFAOYSA-N |
SMILES | O=C(O)CCC(C1=CC=C(OCC)C(OCC)=C1OCC)=O |
Reference | 1: Akiyama Y, Yoshioka M, Horibe H, Hirai S, Kitamori N, Toguchi H. pH independent controlled-release microspheres using polyglycerol esters of fatty acids. J Pharm Sci. 1994 Nov;83(11):1600-7. PubMed PMID: 7891282. |