For research use only. Not for therapeutic Use.
Triadimefon（Cat No.:R016952）is a systemic fungicide used in agriculture to control various fungal diseases in crops like cereals, fruits, and vegetables. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal growth. Effective against rusts, blights, and molds, Triadimefon is often applied as a foliar spray. It is known for its relatively low toxicity to humans and animals, but care should be taken to follow application guidelines to avoid environmental impact. It is also studied for its potential effects on plant stress responses.
| Catalog Number | R016952 |
| CAS Number | 43121-43-3 |
| Synonyms | Triadimephon; Tripinacloraz; Webeton; 1-(4-Chlorophenoxy)-3,3-dimethyl-1,2,4-triazol-1-yl-2-butanone; 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanone; 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1-H-1,2,4-triazol-1-yl)butanone; 1-(4-Chloro |
| Molecular Formula | C14H16ClN3O2 |
| Purity | ≥95% |
| Target | Fungal |
| Storage | -20°C |
| IUPAC Name | 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one |
| InChI | InChI=1S/C14H16ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,13H,1-3H3 |
| InChIKey | WURBVZBTWMNKQT-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(=O)C(N1C=NC=N1)OC2=CC=C(C=C2)Cl |
| Reference | </br>1:Tissue distribution and metabolism of triadimefon and triadimenol enantiomers in Chinese lizards (Eremias argus). Li J, Wang Y, Li W, Xu P, Guo B, Li J, Wang H.Ecotoxicol Environ Saf. 2017 Apr 20;142:284-292. doi: 10.1016/j.ecoenv.2017.04.035. [Epub ahead of print] PMID: 28433593 </br>2:Zebrafish as an Alternative Vertebrate Model for Investigating Developmental Toxicity-The Triadimefon Example. Zoupa M, Machera K.Int J Mol Sci. 2017 Apr 12;18(4). pii: E817. doi: 10.3390/ijms18040817. PMID: 28417904 Free PMC Article</br>3:Disruption of sex-hormone levels and steroidogenic-related gene expression on Mongolia Racerunner (Eremias argus) after exposure to triadimefon and its enantiomers. Li J, Chang J, Li W, Guo B, Li J, Wang H.Chemosphere. 2017 Mar;171:554-563. doi: 10.1016/j.chemosphere.2016.12.096. Epub 2016 Dec 22. PMID: 28039834 </br>4:Stereoselective bioaccumulation, transformation, and toxicity of triadimefon in Scenedesmus obliquus. Xu P, Huang L.Chirality. 2017 Feb;29(2):61-69. doi: 10.1002/chir.22671. Epub 2016 Dec 23. PMID: 28009445 </br>5:The fungicide triadimefon affects beer flavor and composition by influencing Saccharomyces cerevisiae metabolism. Kong Z, Li M, An J, Chen J, Bao Y, Francis F, Dai X.Sci Rep. 2016 Sep 15;6:33552. doi: 10.1038/srep33552. PMID: 27629523 Free PMC Article</br>6:Impact of co-exposure with butachlor and triadimefon on thyroid endocrine system in larval zebrafish. Cao C, Wang Q, Jiao F, Zhu G.Exp Toxicol Pathol. 2016 Sep;68(8):463-9. doi: 10.1016/j.etp.2016.07.004. Epub 2016 Jul 29. PMID: 27480594 </br>7:An Integrated Experimental and Computational Approach for Characterizing the Kinetics and Mechanism of Triadimefon Racemization. Cheng Q, Teng Q, Marchitti SA, Dillingham CM, Kenneke JF.Chirality. 2016 Sep;28(9):633-41. doi: 10.1002/chir.22622. Epub 2016 Aug 1. PMID: 27479933 </br>8:Waterborne exposure to triadimefon causes thyroid endocrine disruption and developmental delay in Xenopus laevis tadpoles. Li M, Li S, Yao T, Zhao R, Wang Q, Zhu G.Aquat Toxicol. 2016 Aug;177:190-7. doi: 10.1016/j.aquatox.2016.05.018. Epub 2016 May 24. PMID: 27289584 </br>9:Behavior of field-applied triadimefon, malathion, dichlorvos, and their main metabolites during barley storage and beer processing. Kong Z, Li M, Chen J, Gui Y, Bao Y, Fan B, Jian Q, Francis F, Dai X.Food Chem. 2016 Nov 15;211:679-86. doi: 10.1016/j.foodchem.2016.05.058. Epub 2016 May 11. PMID: 27283683 </br>10:The regulation of transcriptome responses in zebrafish embryo exposure to triadimefon. Hsu LS, Chiou BH, Hsu TW, Wang CC, Chen SC.Environ Toxicol. 2017 Jan;32(1):217-226. doi: 10.1002/tox.22227. Epub 2016 Jan 20. PMID: 26790661 |
