Triapine (3-AP)

• CAT Number: R060665
• CAS Number: 200933-27-3
• Molecular Formula: C7H9N5S
• Molecular Weight: 195.24
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: C1=CC(=C(N=C1)C=NNC(=S)N)N

Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.

Reference

[1] Finch RA, et al. Biochem Pharmacol. 2000, 59(8), 983-991.
[2] Jiang ZG, et al. CNS Drug Rev. 2006, 12(1), 77-90.