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87-10-5-Tribromsalan Tribromsalan

Tribromsalan

For research use only. Not for therapeutic Use.

  • CAT Number: I037481
  • CAS Number: 87-10-5
  • Molecular Formula: C13H8Br3NO2
  • Molecular Weight: 449.92
  • Purity: 98%
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Related Small Molecules: Ki16198     Anti-TLR7     (+)-Bicuculline    

Tribromsalan is Germicide.


Catalog Number I037481
CAS Number 87-10-5
Synonyms

Agramed, AI3-25516, ASC-4, BRN 2146888, Caswell No. 863, CCRIS 5745, ENT 25516, EPA Pesticide Chemical Code 077404, ET-394, Sherstat TBS, Stecker asc-4, TBS, TBS 95, Tribromsalan, Temasept II, Temasept IV, Tribromosalicylanilide, Trisanil, Tuasol 100, Vancide TBS, WR 34912

Molecular Formula C13H8Br3NO2
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 3,5-Dibromo-N-(4-bromophenyl)-2-hydroxybenzamide
InChI InChI=1S/C13H8Br3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)
InChIKey KVSKGMLNBAPGKH-UHFFFAOYSA-N
SMILES O=C(NC1=CC=C(Br)C=C1)C2=CC(Br)=CC(Br)=C2O
Reference

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2: Miller SC, Huang R, Sakamuru S, Shukla SJ, Attene-Ramos MS, Shinn P, Van Leer D, Leister W, Austin CP, Xia M. Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action. Biochem Pharmacol. 2010 May 1;79(9):1272-80. doi: 10.1016/j.bcp.2009.12.021. Epub 2010 Jan 11. PubMed PMID: 20067776; PubMed Central PMCID: PMC2834878.
3: Fujinuma K, Takeba K, Kamata K. [Concentration in plasma and excretion in milk of lactating cows after oral administration of tribromsalan, oxyclozanide and bromofenofos]. Shokuhin Eiseigaku Zasshi. 2006 Dec;47(6):249-53. Japanese. PubMed PMID: 17228788.
4: Durbize E, Vigan M, Puzenat E, Girardin P, Adessi B, Desprez PH, Humbert PH, Laurent R, Aubin F. Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen: associated photoallergies to non-benzophenone-containing molecules. Contact Dermatitis. 2003 Mar;48(3):144-9. PubMed PMID: 12755728.
5: Takeba K, Itoh T, Matsumoto M, Nakazawa H, Tanabe S. Simultaneous determination of five fasciolicides in milk by liquid chromatography with electrochemical detection. J AOAC Int. 1996 Jul-Aug;79(4):848-52. PubMed PMID: 8757441.
6: Vohr HW, Homey B, Schuppe HC, Kind P. Detection of photoreactivity demonstrated in a modified local lymph node assay in mice. Photodermatol Photoimmunol Photomed. 1994 Apr;10(2):57-64. PubMed PMID: 8043386.
7: Xia Q, Tan P, Feng X, Chen M, Kajihara N, Minai M, Hosaka Y. Assessment of the molluscicidal activities of Tribromosalan, Cartap and Chlorothalonil against Oncomelania hupensis. Jpn J Med Sci Biol. 1992 Apr;45(2):75-80. PubMed PMID: 1434068.
8: Miyauchi H, Horio T. A new animal model for contact dermatitis: the hairless guinea pig. J Dermatol. 1992 Mar;19(3):140-5. PubMed PMID: 1640019.
9: Duschet P, Schwarz T, Oppolzer G, Gschnait F. Persistent light reaction. Successful treatment with cyclosporin A. Acta Derm Venereol. 1988;68(2):176-8. PubMed PMID: 2454004.
10: Yoshimura H, Nakamura M, Koeda T. Lack of mutagenicity of fasciolicides. Vet Res Commun. 1985 Apr;9(2):147-52. PubMed PMID: 4002614.
11: Miyachi Y, Takigawa M. Mechanisms of contact photosensitivity in mice. III. Predictive testing of chemicals with photoallergenic potential in mice. Arch Dermatol. 1983 Sep;119(9):736-9. PubMed PMID: 6614960.
12: Horio T. Actinic reticuloid via persistent light reaction from photoallergic contact dermatitis. Arch Dermatol. 1982 May;118(5):339-42. PubMed PMID: 7082027.
13: Jordan WP Jr. The guinea pig as a model for predicting photoallergic contact dermatitis. Contact Dermatitis. 1982 Mar;8(2):109-16. PubMed PMID: 7067446.
14: De Vries H, Beijersbergen van Henegouwen GM. The influence of glutathione on the photoreaction of 3,4′,5-tribromosalicylanilide alone and in the presence of serum albumin. Pharm Weekbl Sci. 1981 Dec 18;3(6):258-62. PubMed PMID: 7329770.
15: Coburn RA, Batista AJ, Evans RT, Genco RJ. Potential salicylamide antiplaque agents: in vitro antibacterial activity against Actinomyces viscosus. J Med Chem. 1981 Oct;24(10):1245-9. PubMed PMID: 7328586.
16: Norbury HM, Waring RH. The disposition and metabolism of 3,4′,5-tribromosalicylanilide and 4’5-dibromosalicylanilide in the rat. Xenobiotica. 1981 Jul;11(7):501-8. PubMed PMID: 7293237.
17: Cruthers LR, James TM, Goff S. Efficacy of a tribromosalan and parbendazole composition against adult Fasciola hepatica in sheep. Res Vet Sci. 1981 Jan;30(1):122-3. PubMed PMID: 6894647.
18: Condie LW, Buhler DR. Effect of hexachlorophene, tribromsalan, trichlorcarban and cloflucarban on hexobarbital sleeping time and hepatic drug-metabolizing enzyme activity in vitro in the rat. Biochem Pharmacol. 1979;28(3):375-80. PubMed PMID: 426854.
19: Chun Hong HS, Steltenkamp RJ, Smith NL. Quantitative analysis of tribromsalan in blood and urine. J Pharm Sci. 1975 Dec;64(12):2007-8. PubMed PMID: 1513.
20: Shelmire D. False negative immediate photopatch test to tribromsalan. Arch Dermatol. 1971 Feb;103(2):223-4. PubMed PMID: 5552349.

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