For research use only. Not for therapeutic Use.
Triclofos Sodium, also known as Triclofos and SCH-10159, is a drug used to treat insomnia and used for sedation.
| Catalog Number | I009880 |
| CAS Number | 7246-20-0 |
| Synonyms | Triclofos Sodium; SCH-10159; SCH 10159; SCH10159;sodium 2,2,2-trichloroethyl hydrogen phosphate |
| Molecular Formula | C2H3Cl3NaO4P |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | -20°C |
| IUPAC Name | sodium;2,2,2-trichloroethyl hydrogen phosphate |
| InChI | InChI=1S/C2H4Cl3O4P.Na/c3-2(4,5)1-9-10(6,7)8;/h1H2,(H2,6,7,8);/q;+1/p-1 |
| InChIKey | WFKJEZKHPGDCRK-UHFFFAOYSA-M |
| SMILES | C(C(Cl)(Cl)Cl)OP(=O)(O)[O-].[Na+] |
| Reference | </br>1:Evaluation of nitrous oxide-oxygen and triclofos sodium as conscious sedative agents. Subramaniam P, Girish Babu KL, Lakhotia D.J Indian Soc Pedod Prev Dent. 2017 Apr-Jun;35(2):156-161. doi: 10.4103/JISPPD.JISPPD_82_16. PMID: 28492195 Free Article</br>2:Efficacy of midazolam as oral premedication in children in comparison to triclofos sodium. Radhika KP, Sreejit MS, Ramadas KT.Indian J Anaesth. 2016 Jun;60(6):415-9. doi: 10.4103/0019-5049.183389. PMID: 27330204 Free PMC Article</br>3:Multilocalized non-pigmenting fixed drug eruption caused by triclofos sodium. Fujimoto W, Matsuo-Kanda A.Eur J Dermatol. 2014 May-Jun;24(3):380-1. doi: 10.1684/ejd.2014.2314. No abstract available. PMID: 24721678 </br>4:Transient administration of triclofos sodium is helpful in minimizing anticonvulsants under polypharmacy. Sakai H, Kirino E, Inoue R, Arai H.Psychiatry Clin Neurosci. 2006 Dec;60(6):776-7. No abstract available. PMID: 17109718 Free Article</br>5:The effect of triclofos sodium sedation on respiratory rate, oxygen saturation, and heart rate in infants and young children. Jackson EA, Rabbette PS, Dezateux C, Hatch DJ, Stocks J.Pediatr Pulmonol. 1991;10(1):40-5. PMID: 2003045 </br>6:Comparative trial of a new hypnotic (Finorgal) with nitrazepam and triclofos sodium. Baiotti G.J Int Med Res. 1979;7(5):383-6. PMID: 387491 </br>7:Hydrolysis kinetics of the monophosphate ester triclofos sodium. McRae JD, Tadros LM.J Pharm Sci. 1978 May;67(5):631-5. PMID: 25331 </br>8:Triclofos sodium (Triclos) for insomnia. [No authors listed]Med Lett Drugs Ther. 1972 Oct 13;14(21):78-80. No abstract available. PMID: 4567567 </br>9:Electroencephalographic evaluation of triclofos sodium sedation in children. Millichap JG.Am J Dis Child. 1972 Oct;124(4):526-7. No abstract available. PMID: 4638712 |
