For research use only. Not for therapeutic Use.
Triclosan(Cat No.:A000050)is a broad-spectrum antimicrobial agent commonly used in personal care products, including soaps, toothpaste, and deodorants. It functions by inhibiting bacterial fatty acid synthesis, making it effective against a wide range of Gram-positive and Gram-negative bacteria. Despite its widespread use, concerns have arisen regarding its environmental impact and potential role in promoting antibiotic resistance. Triclosan has also been scrutinized for its endocrine-disrupting effects, particularly in aquatic organisms. While its use in some consumer products has been restricted, it remains a key ingredient in certain healthcare and industrial applications.
Catalog Number | A000050 |
CAS Number | 3380-34-5 |
Synonyms | Irgasan, Cloxifenolum |
Molecular Formula | C12H7Cl3O2 |
Purity | ≥95% |
Target | Antibiotic |
Solubility | Soluble in DMSO |
Storage | Room temperature |
IUPAC Name | 5-chloro-2-(2,4-dichlorophenoxy)phenol |
InChI | InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H |
InChIKey | XEFQLINVKFYRCS-UHFFFAOYSA-N |
SMILES | C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl |
Reference | 1: Pan CG, Peng FJ, Shi WJ, Hu LX, Wei XD, Ying GG. Triclosan-induced <br> 3: Webber MA, Buckner MMC, Redgrave LS, Ifill G, Mitchenall LA, Webb C, Iddles R, <br> 5: Han J, Qiu W, Campbell EC, White JC, Xing B. Nylon Bristles and Elastomers 6: Pavez L, Tobar N, Chacón C, Arancibia R, Martínez C, Tapia C, Pastor A, 7: Lu S, Yu Y, Ren L, Zhang X, Liu G, Yu Y. Estimation of intake and uptake of 8: Henriksen NA, Deerenberg EB, Venclauskas L, Fortelny RH, Garcia-Alamino JM, 9: Ding T, Lin K, Yang M, Bao L, Li J, Yang B, Gan J. Biodegradation of triclosan 10: Wang F, Guo X, Chen W, Sun Y, Fan C. Effects of triclosan on hormones and |