For research use only. Not for therapeutic Use.
Trifluoromethyl-tubercidin(CAT: I040685) is a fluorinated nucleoside analog derived from tubercidin, featuring a trifluoromethyl (-CF₃) group that enhances its lipophilicity, metabolic stability, and cell membrane permeability. This modification improves its pharmacological profile, making it a potent agent against viral, cancerous, and parasitic cells by interfering with nucleic acid synthesis and adenosine-related pathways. Trifluoromethyl-tubercidin is incorporated into DNA or RNA, disrupting replication and transcription. It is widely utilized in drug discovery and medicinal chemistry for exploring nucleoside analog mechanisms and developing new therapeutic strategies for rapidly proliferating diseases. Its unique structure makes it a valuable tool in biochemical and pharmacological research.
| CAS Number | 1854086-05-7 |
| Synonyms | (2R,3R,4S,5R)-2-[4-amino-5-(trifluoromethyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
| Molecular Formula | C12H13F3N4O4 |
| Purity | ≥95% |
| IUPAC Name | (2R,3R,4S,5R)-2-[4-amino-5-(trifluoromethyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
| InChI | InChI=1S/C12H13F3N4O4/c13-12(14,15)4-1-19(10-6(4)9(16)17-3-18-10)11-8(22)7(21)5(2-20)23-11/h1,3,5,7-8,11,20-22H,2H2,(H2,16,17,18)/t5-,7-,8-,11-/m1/s1 |
| InChIKey | RSOXZOFDCJMRMK-IOSLPCCCSA-N |
| SMILES | C1=C(C2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
