Trimetaphan camsilate

• CAT Number: I009884
• CAS Number: 68-91-7
• Molecular Formula: C32H40N2O5S2
• Molecular Weight: 596.80
• Purity: ≥95%
• Synonyms: Trimethaphan; Trimetaphan camsilate; Trimetaphan camsilate (INN) or trimethaphan camsylate (USAN), trade name Arfonad.;1,3-dibenzyl-2-oxodecahydrothieno[1/’,2/’:1,2]thieno[3,4-d]imidazol-5-ium ((1R,4S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)meth
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: 3,5-dibenzyl-8-thionia-3,5-diazatricyclo[6.3.0.02,6]undecan-4-one;(7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methanesulfonate
• InChI: InChI=1S/C22H25N2OS.C10H16O4S/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h1-6,8-11,19-21H,7,12-16H2;7H,3-6H2,1-2H3,(H,12,13,14)/q+1;/p-1/t;7-,10-/m.0/s1
• InChIKey: HALWUDBBYKMYPW-JAGIHPHKSA-M
• SMILES: CC1(C2CCC1(C(=O)C2)CS(=O)(=O)[O-])C.C1CC2C3C(C[S+]2C1)N(C(=O)N3CC4=CC=CC=C4)CC5=CC=CC=C5

Trimetaphan Camsilate(CAT: I009884) is a short-acting ganglionic blocker that inhibits nicotinic acetylcholine receptors at autonomic ganglia. By interrupting sympathetic and parasympathetic nerve transmission, it induces controlled hypotension and is primarily used in research focused on cardiovascular regulation. Its mechanism of action makes it valuable for studies on blood pressure management, autonomic nervous system dysfunctions, and vascular responses. Trimetaphan Camsilate is particularly relevant in pharmacological and physiological investigations, providing insights into ganglionic transmission and potential therapeutic strategies for cardiovascular disorders.