For research use only. Not for therapeutic Use.
Trimetazidine-d8 Dihydrochloride (Cat No.:C000877) is a deuterated derivative of Trimetazidine Dihydrochloride, a medication used to treat angina pectoris and other heart conditions. The “-d8” in the compound’s name indicates that eight hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. This labeling is often used in pharmaceutical research to study the metabolism and pharmacokinetics of the drug. Deuterated compounds allow researchers to track the fate of the drug in the body and determine its metabolic pathways. Trimetazidine-d8 Dihydrochloride is valuable in understanding the pharmacological and pharmacokinetic properties of Trimetazidine Dihydrochloride.
| Catalog Number | C000877 |
| CAS Number | 1219795-37-5 |
| Synonyms | 1-[(2,3,4-Trimethoxy-phenyl)methyl]piperazine-d8 Dihydrochloride; |
| Molecular Formula | C₁₄H₁₆D₈Cl₂N₂O₃ |
| Purity | ≥95% |
| Target | Autophagy |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | White to Off-White Solid |
| Storage | -20°C, Hygroscopic |
| IUPAC Name | 2,2,3,3,5,5,6,6-octadeuterio-1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride |
| InChI | InChI=1S/C14H22N2O3.2ClH/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16;;/h4-5,15H,6-10H2,1-3H3;2*1H/i6D2,7D2,8D2,9D2;; |
| InChIKey | VYFLPFGUVGMBEP-IKGFOUCPSA-N |
| SMILES | COC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC.Cl.Cl |
| Reference | Fujita, et al.: Jpn. J. Pharmacol., 17, 19 (1967), Harpey, C., et al.: Cardiovasc. Drug Rev., 6, 292 (1989), |
