Trimethobenzamide HCl

• CAT Number: I009885
• CAS Number: 554-92-7 (HCl salt)
• Molecular Formula: C21H29ClN2O5
• Molecular Weight: 424.92
• Purity: ≥95%
• Synonyms: Tebamide; Ticon; Tigan; trimethobenzamide; trimethobenzamide monohydrochloride; trade names Tebamide, Tigan.;N-{[4-(2-dimethylaminoethoxy)phenyl]methyl}-3,4,5-trimethoxy-benzamide hydrochloride
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide;hydrochloride
• InChI: InChI=1S/C21H28N2O5.ClH/c1-23(2)10-11-28-17-8-6-15(7-9-17)14-22-21(24)16-12-18(25-3)20(27-5)19(13-16)26-4;/h6-9,12-13H,10-11,14H2,1-5H3,(H,22,24);1H
• InChIKey: WIIZEEPFHXAUND-UHFFFAOYSA-N
• SMILES: CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C(=C2)OC)OC)OC.Cl

Trimethobenzamide hydrochloride (Cat No.:I009885) is an antiemetic used to prevent and treat nausea and vomiting, particularly those associated with gastrointestinal disorders and chemotherapy. It works by blocking dopamine receptors in the brain’s chemoreceptor trigger zone, which helps reduce nausea. Typically administered orally or via injection, it has a moderate onset of action. Common side effects include drowsiness, dizziness, and headache. It is generally well-tolerated but should be used cautiously in patients with a history of seizures or heart problems. Trimethobenzamide is contraindicated in individuals with hypersensitivity to the drug.