For research use only. Not for therapeutic Use.
Triparanol (MER-29) is an inhibitor of 24-dehydrocholesterol reductase (DHCR24), an enzyme involved in cholesterol biosynthesis. It exhibits antitumor properties, such as decreasing proliferation and inducing apoptosis in various cancer cell lines, while also reducing Hedgehog pathway signaling in these cells.
Catalog Number | R009398 |
CAS Number | 78-41-1 |
Molecular Formula | C27H32ClNO2 |
Purity | ≥95% |
Reference | [1] Bi X, et al. Biochem Biophys Res Commun. 2012 Aug 31;425(3):613-8. |