Tripeptide-10 citrulline

  • CAT Number: I037538
  • CAS Number: 960531-53-7
  • Molecular Formula: C22H42N8O7
  • Molecular Weight: 530.63
  • Purity: 98%
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Tripeptide-10 Citrulline is a new cosmetic active, designed as a substitute of decorin, that specifically targets collagen fibre organization to regulate collagen fibrillogenesis.


Catalog Number I037538
CAS Number 960531-53-7
Synonyms

Tripeptide-10 citrulline; Decorinyl; UNII-2732R0E76W.

Molecular Formula C22H42N8O7
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name L-Ornithinamide, L-lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-
InChI InChI=1S/C22H42N8O7/c1-3-12(2)17(21(36)28-14(18(25)33)8-6-10-27-22(26)37)30-20(35)15(11-16(31)32)29-19(34)13(24)7-4-5-9-23/h12-15,17H,3-11,23-24H2,1-2H3,(H2,25,33)(H,28,36)(H,29,34)(H,30,35)(H,31,32)(H3,26,27,37)/t12-,13-,14-,15-,17-/m0/s1
InChIKey GKPMARPRXONRJX-BWJWTDLKSA-N
SMILES O=C(N)[C@H](CCCNC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H](CCCCN)N)=O)=O)=O
Reference

1: Raikou V, Varvaresou A, Panderi I, Papageorgiou E. The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study. J Cosmet Dermatol. 2017 Jun;16(2):271-278. doi: 10.1111/jocd.12314. Epub 2017 Feb 2. PubMed PMID: 28150423.
2: Puig A, Antón JM, Mangues M. A new decorin-like tetrapeptide for optimal organization of collagen fibres. Int J Cosmet Sci. 2008 Apr;30(2):97-104. doi: 10.1111/j.1468-2494.2008.00429.x. PubMed PMID: 18377618.

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