For research use only. Not for therapeutic Use.
Triptophenolide(CAT: I004758) is a diterpenoid epoxide derived from Tripterygium wilfordii (thunder god vine), known for its potent anti-inflammatory and immunosuppressive properties. This compound acts through multiple pathways, including the inhibition of NF-κB signaling, a key regulator of inflammation and immune responses. Triptophenolide has shown significant efficacy in preclinical studies for autoimmune diseases, cancer, and chronic inflammatory disorders. Its ability to modulate immune cell activity and cytokine production makes it a valuable tool for investigating molecular mechanisms underlying inflammation and immune dysregulation. Triptophenolide continues to be explored for its therapeutic potential in pharmacological and biomedical research.
| Catalog Number | I004758 |
| CAS Number | 74285-86-2 |
| Molecular Formula | C20H24O3 |
| Purity | ≥95% |
| Target | Androgen Receptor |
| Solubility | 10 mM in DMSO |
| Storage | Store at RT |
| IUPAC Name | (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one |
| InChI | InChI=1S/C20H24O3/c1-11(2)12-4-6-16-14(18(12)21)5-7-17-15-10-23-19(22)13(15)8-9-20(16,17)3/h4,6,11,17,21H,5,7-10H2,1-3H3/t17-,20+/m0/s1 |
| InChIKey | KPXIBWGPZSPABK-FXAWDEMLSA-N |
| SMILES | CC(C)C1=C(C2=C(C=C1)[C@]3(CCC4=C([C@@H]3CC2)COC4=O)C)O |
