Tromantadine

For research use only. Not for therapeutic Use.

  • CAT Number: I013361
  • CAS Number: 53783-83-8
  • Molecular Formula: C₁₆H₂₈N₂O₂
  • Molecular Weight: 280.41
  • Purity: ≥95%
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Tromantadine(Cat No.:I013361)is an antiviral medication primarily used to treat influenza (flu) infections. It works by inhibiting the replication of the influenza virus, specifically by interfering with the uncoating process of the virus, which is essential for its ability to replicate inside host cells. Tromantadine belongs to the class of adamantane derivatives, similar to amantadine, but with improved efficacy and a potentially more favorable side effect profile. It is used to reduce the severity and duration of flu symptoms when taken early in the infection. Tromantadine is not approved in all regions and may be subject to regional regulatory review.


Catalog Number I013361
CAS Number 53783-83-8
Molecular Formula C₁₆H₂₈N₂O₂
Purity ≥95%
Target HSV
Solubility DMSO
IUPAC Name N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide
InChI InChI=1S/C16H28N2O2/c1-18(2)3-4-20-11-15(19)17-16-8-12-5-13(9-16)7-14(6-12)10-16/h12-14H,3-11H2,1-2H3,(H,17,19)
InChIKey UXQDWARBDDDTKG-UHFFFAOYSA-N
SMILES CN(C)CCOCC(=O)NC12CC3CC(C1)CC(C3)C2
Reference

[1]. Rosenthal KS, et al. Tromantadine: inhibitor of early and late events in herpes simplex virus replication. Antimicrob Agents Chemother. 1982 Dec;22(6):1031-6.<br>[2]. Cheetham JJ, et al. Comparison of the interaction of the anti-viral chemotherapeutic agents amantadine and tromantadine with model phospholipid membranes. Biosci Rep. 1987 Mar;7(3):225-30.

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