For research use only. Not for therapeutic Use.
Tropisetron HCl is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.<br>Tropisetron is a high affinity ligand for both th α7 nAChR and 5HT3R. Tropisetron has very low affinity for the other nicotinic subtypes tested.<br>Tropisetron (1 mg/kg i.p.) significantly improves the deficient inhibitory processing of the P20-N40 auditory evoked potential in DBA/2 mice.
| Catalog Number | A001083 |
| CAS Number | 105826-92-4 |
| Synonyms | ICS 205-930 |
| Molecular Formula | C17H20N2O2 • HCl |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO |
| Storage | 3 years -20C powder |
| InChIKey | XIEGSJAEZIGKSA-LUNMCBQDSA-N |
