TROVAFLOXACIN

• CAT Number: M091062
• CAS Number: 147059-72-1
• Molecular Formula: C20H15F3N4O3
• Molecular Weight: 416.36
• Purity: ≥95%
• Target: Cell Cycle/DNA Damage
• Storage: -20°C
• IUPAC Name: 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• InChI: InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16?
• InChIKey: WVPSKSLAZQPAKQ-SOSAQKQKSA-N
• SMILES: C1[C@@H]2[C@@H](C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F

Trovafloxacin（Cat No.:M091062）is a broad-spectrum fluoroquinolone antibiotic effective against a variety of Gram-positive and Gram-negative bacteria, including those causing respiratory, urinary, and intra-abdominal infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription, leading to bacterial cell death. While initially promising, trovafloxacin use was significantly restricted due to its association with rare but severe liver toxicity. Despite these limitations, it remains a valuable study compound in antibiotic research, especially for understanding fluoroquinolone efficacy and safety mechanisms.