Trovafloxacin Mesylate

• CAT Number: R051197
• CAS Number: 147059-75-4
• Molecular Formula: C21H19F3N4O6S
• Molecular Weight: 512.46
• Purity: ≥95%
• Synonyms: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trov
• Target: Cell Cycle/DNA Damage
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at RT
• IUPAC Name: 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
• InChI: InChI=1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16?
• InChIKey: DYNZICQDCVYXFW-GIPYJWDTSA-N
• SMILES: CS(=O)(=O)O.C1[C@@H]2[C@@H](C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F

Trovafloxacin Mesylate（Cat No.:R051197）is a synthetic fluoroquinolone antibiotic with broad-spectrum activity, particularly effective against Gram-positive, Gram-negative, and anaerobic bacteria. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, which ultimately leads to bacterial cell death. Initially used for treating serious infections like intra-abdominal, respiratory, and skin infections, it showed efficacy against drug-resistant pathogens. However, due to concerns about hepatotoxicity, its use has been limited to specific, life-threatening cases under careful supervision. Trovafloxacin Mesylate remains significant in research on antibiotic resistance and drug safety.