For research use only. Not for therapeutic Use.
Troxipide (Cat.No:I003086) is a gastroprotective drug used for the treatment of gastrointestinal disorders, including gastritis and peptic ulcers. It works by promoting mucosal protection, reducing inflammation, and increasing the secretion of protective substances in the gastrointestinal tract. Troxipide has shown efficacy in relieving symptoms and promoting healing in various gastrointestinal conditions.
| Catalog Number | I003086 |
| CAS Number | 30751-05-4 |
| Molecular Formula | C15H22N2O4 |
| Purity | ≥95% |
| Solubility | DMSO:10mg/mL |
| Storage | 3 years -20℃powder |
| IUPAC Name | 3,4,5-trimethoxy-N-piperidin-3-ylbenzamide |
| InChI | InChI=1S/C15H22N2O4/c1-19-12-7-10(8-13(20-2)14(12)21-3)15(18)17-11-5-4-6-16-9-11/h7-8,11,16H,4-6,9H2,1-3H3,(H,17,18) |
| InChIKey | YSIITVVESCNIPR-UHFFFAOYSA-N |
| SMILES | COC1=CC(=CC(=C1OC)OC)C(=O)NC2CCCNC2 |
| Reference | </br>1:Design and evaluation of polyox and pluronic controlled gastroretentive delivery of troxipide. Jagdale SC, Kamble SB, Kuchekar BS, Chabukswar AR.J Drug Deliv. 2014;2014:804616. doi: 10.1155/2014/804616. Epub 2014 Nov 19. PMID: 25505995 Free PMC Article</br>2:Preparation and pharmacokinetics study on gastro-floating sustained-release tablets of troxipide. Gao Y, Gao Y, Yin F, Wang M, Wang Z, Ye T, Yang Y, Pan WS, Yang X.Drug Dev Ind Pharm. 2015;41(9):1443-51. doi: 10.3109/03639045.2014.956113. Epub 2015 Jul 21. PMID: 25190152 </br>3:Troxipide in the management of gastritis: a randomized comparative trial in general practice. Dewan B, Balasubramanian A.Gastroenterol Res Pract. 2010;2010:758397. doi: 10.1155/2010/758397. Epub 2010 Nov 25. PMID: 21127703 Free PMC Article</br>4:Troxipide, a novel antiulcer compound, has inhibitory effects on human neutrophil migration and activation induced by various stimulants. Kusugami K, Ina K, Hosokawa T, Kobayashi F, Kusajima H, Momo K, Nishio Y.Dig Liver Dis. 2000 May;32(4):305-11. PMID: 11515628 </br>5:[Preventive effects of troxipide on a newly developed model of acute gastric mucosal lesion (AGML) induced by ischemia/reperfusion plus ammonia in the rat]. Momo K, Hoshina K, Ishibashi Y, Saito T.Nihon Yakurigaku Zasshi. 1994 Oct;104(4):313-23. Japanese. PMID: 7959422 </br>6:[The pharmacodynamics of troxipide on experimental gastric ulcers in rats]. Wang J, Zhang L, Fang Z, Fan A, Wang Y.Hua Xi Yi Ke Da Xue Xue Bao. 1993 Sep;24(3):313-6. Chinese. PMID: 8288208 </br>7:[Effects of troxipide on acute gastric lesions in rats]. Sekiguchi H, Hamada K, Okada Y, Taga F.Nihon Yakurigaku Zasshi. 1987 Mar;89(3):111-9. Japanese. PMID: 3583134 |
