TT-10

• CAT Number: I037579
• CAS Number: 2230640-94-3
• Molecular Formula: C11H10FN3OS2
• Molecular Weight: 283.35
• Purity: ≥95%
• Synonyms: [4-amino-2-(prop-2-enylamino)-1,3-thiazol-5-yl]-(5-fluorothiophen-2-yl)methanone
• InChI: InChI=1S/C11H10FN3OS2/c1-2-5-14-11-15-10(13)9(18-11)8(16)6-3-4-7(12)17-6/h2-4H,1,5,13H2,(H,14,15)
• InChIKey: GVYPHJQPOHDZEI-UHFFFAOYSA-N
• SMILES: C=CCNC1=NC(=C(S1)C(=O)C2=CC=C(S2)F)N

TT-10（Cat No.:I037579）is a potent synthetic peptide that acts as an inhibitor of the immune checkpoint protein PD-1 (Programmed Cell Death-1). By blocking the PD-1 pathway, TT-10 enhances T-cell activation and immune response, allowing the body’s immune system to better recognize and attack cancer cells. This compound is being explored as a potential therapeutic agent in oncology, particularly in cancers that have developed resistance to immune checkpoint inhibitors. TT-10 shows promise in combination therapies aimed at boosting the effectiveness of immunotherapy for various malignancies.