For research use only. Not for therapeutic Use.
Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively[1].
| Catalog Number | I040461 |
| CAS Number | 793729-44-9 |
| Synonyms | 2-(4-fluorophenyl)-5-[[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-1,3,4-oxadiazole |
| Molecular Formula | C15H9FN4O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C15H9FN4O3S/c16-10-5-3-9(4-6-10)13-18-17-12(22-13)8-24-15-20-19-14(23-15)11-2-1-7-21-11/h1-7H,8H2 |
| InChIKey | RDVSQKOJZWNWAZ-UHFFFAOYSA-N |
| SMILES | C1=COC(=C1)C2=NN=C(O2)SCC3=NN=C(O3)C4=CC=C(C=C4)F |
| Reference | [1]. Early JV, et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2016 May 23;60(6):3608-16. |
