Tubulin inhibitor 6

• CAT Number: I015494
• CAS Number: 105925-39-1
• Molecular Formula: C₂₀H₁₄ClNO₂S
• Molecular Weight: 367.85
• Purity: ≥95%
• Target: Cytoskeleton

Tubulin inhibitor 6(CAT: I015494) is a potent tubulin inhibitor with inhibitory effects on multiple cancer cell lines. It exerts its action by inhibiting tubulin polymerization, a crucial process for microtubule formation and cell division. Tubulin inhibitor 6 demonstrates an IC50 value of 0.87 μM for inhibiting tubulin polymerization. By disrupting microtubule dynamics, it interferes with cell division and proliferation, making it a potential candidate for anti-cancer therapy.

Reference

[1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.