For research use only. Not for therapeutic Use.
TUG-1375 (CAT: I019340) is an agonist of the free fatty acid receptor 2 (FFA2/GPR43). Free fatty acid receptors are G protein-coupled receptors that are activated by short-chain fatty acids, which are products of bacterial fermentation in the gut. FFA2 is primarily expressed in immune cells and certain cells of the gastrointestinal tract. When TUG-1375 binds to FFA2, it triggers a signaling cascade that can influence various cellular responses, including immune modulation and metabolic regulation.
| Catalog Number | I019340 |
| CAS Number | 2247372-59-2 |
| Molecular Formula | C₂₂H₁₉ClN₂O₄S |
| Purity | ≥95% |
| Target | Free Fatty Acid Receptor |
| Reference | [1]. Hansen AH, et al. Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties. J Med Chem. 2018 Nov 8;61(21):9534-9550. |
