For research use only. Not for therapeutic Use.
Tunicamycin（Cat No.:I000442）is a naturally occurring antibiotic that inhibits N-linked glycosylation in eukaryotic cells by blocking the formation of N-acetylglucosamine-1-phosphate transferase. This disruption of protein glycosylation leads to the accumulation of misfolded proteins, triggering the unfolded protein response (UPR) and causing cell stress. Tunicamycin is widely used in research to study protein folding, glycoprotein synthesis, and cellular stress responses. Additionally, it serves as a valuable tool for investigating the mechanisms of diseases related to protein misfolding and glycosylation disorders, making it crucial for advancing biomedical research.
| Catalog Number | I000442 |
| CAS Number | 11089-65-9 |
| Molecular Formula | C₃₈H₆₂N₄O₆ |
| Purity | ≥95% |
| Target | Transferase |
| Solubility | 50 mM in DMSO |
| Storage | Store at +4C |
