Tylosin

For research use only. Not for therapeutic Use.

  • CAT Number: I001532
  • CAS Number: 1401-69-0
  • Molecular Formula: C46H77NO17
  • Molecular Weight: 916.10
  • Purity: ≥95%
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Tylosin(Cat No.:I001532)is a macrolide antibiotic primarily used in veterinary medicine to treat bacterial infections in livestock, such as respiratory, gastrointestinal, and skin infections. It is particularly effective against Gram-positive organisms and certain mycoplasma species. Tylosin works by binding to the 50S ribosomal subunit, inhibiting protein synthesis and stopping bacterial growth. Its applications extend to disease prevention and growth promotion in poultry and swine. Due to its low toxicity and high efficacy, tylosin remains an essential antibiotic in animal husbandry, supporting health and productivity in farm animals.


Catalog Number I001532
CAS Number 1401-69-0
Synonyms

Fradizine; Tylocine; Tylosin A

Molecular Formula C46H77NO17
Purity ≥95%
Target Bacterial
Solubility 10 mM in DMSO
Storage Store at -20C
IUPAC Name 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
InChI InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1
InChIKey WBPYTXDJUQJLPQ-VMXQISHHSA-N
SMILES CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
Reference

<p>
<span style=/font-size:12px;/>[1]. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73.&nbsp;</span>
</p>
<p>
[2]. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95.
</p>

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