Tylosin phosphate

• CAT Number: I001560
• CAS Number: 1405-53-4
• Molecular Formula: C46H80NO21P
• Molecular Weight: 1014.10
• Purity: ≥95%
• Synonyms: 2-[(4R,5S,6S,7R,9R,11E,13Z,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)
• Target: Bacterial
• Solubility: 10 mM in H2O
• Storage: Store at -20°C
• IUPAC Name: 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde;phosphoric acid
• InChI: InChI=1S/C46H77NO17.H3O4P/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;1-5(2,3)4/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;(H3,1,2,3,4)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;/m1./s1
• InChIKey: NBOODGNJLRRJNA-IAGPQMRQSA-N
• SMILES: CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.OP(=O)(O)O

Tylosin Phosphate（Cat No.:I001560）is a macrolide antibiotic widely used in veterinary medicine, especially for swine and poultry, to manage bacterial infections and enhance animal growth. It targets Gram-positive bacteria and certain mycoplasma species by inhibiting protein synthesis through binding to the bacterial ribosome, effectively controlling respiratory and enteric infections. Tylosin phosphate’s stability makes it suitable as a feed additive, promoting weight gain and feed efficiency in livestock. Known for its safety and efficacy, it is a critical tool in maintaining animal health and productivity in agricultural settings.

Reference

[1]. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73.
[2]. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95.